| ORIGINAL ARTICLE |
|
| Year : 2015 | Volume
: 52
| Issue : 4 | Page : 264-269 |
|
|
Migraine comorbidity in patients with multiple sclerosis
Lobna M El-Nabil MD 1, Ghada Ashraf1, Khaled O Abdulghani2, Ayman Nasef1, Mohammad Ossama Abdulghani1
1 Department of Neurology, Ain Shams University, Cairo, Egypt
2 Department of Neurology, Helwan University, Cairo, Egypt
Correspondence Address:
Lobna M El-Nabil
Department of Neurology, Ain Shams University, 11539 Cairo
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1110-1083.170659
|
|
|
Background
Migraine headache is a common feature in multiple sclerosis (MS) patients, with variable prevalence among studies. It can influence the diagnosis, radiological evaluation, treatment, and quality of life of these patients.
Objective
The aim of the study was to assess the frequency and severity of migraine in a sample of Egyptian patients with MS and to study the clinical and radiological characteristics in those patients.
Patients and methods
We studied 55 patients with MS. They were subjected to full clinical and neurological assessment, including the diagnosis of migraine. Migraine diagnosis was made using a questionnaire based on criteria proposed by the International Classification of Headache Disorders, 2nd ed. Neurological impairment was evaluated with the Multiple Sclerosis Severity Scale; migraine severity evaluation was made using the Migraine Disability Assessment Scale. MRI of the brain and spinal cord was also performed.
Results
Migraine headache was present in 19 (34.5%) patients. Our results indicate that the majority of patients with coexisting migraine and MS develop migraine years earlier. There was no statistically significant difference between patients with migraine and those without with respect to the age at onset of MS, duration of illness, annual relapse rate, Expanded Disability Status Scale, and Multiple Sclerosis Severity Scale. However, midbrain periaqueductal affection in MRI was more prevalent among MS patients with migraine.
Conclusion
Migraine is comorbid in patients with MS. The exact etiology and pathogenesis of these two seemingly disparate disorders has not been completely understood. |
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
